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AUY-922 - CAS# 747412-49-3 size:2mg solid 1154097-71-8

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Description

1154097-71-8

CAS Number: 1445251-22-8

(2006) Mol Cell Biol

Kulkarni A

AUY-922 - CAS# 747412-49-3 size:2mg solid 1154097-71-8AUY 922, also known as Luminespib, NVP AUY922, VER52296, CAS No. 747412 49 3, is a derivative of 4, 5 diarylisoxazole and a third generation heat shock protein 90 (Hsp90) inhibitor with potential antineoplastic activity. Hsp90 inhibitor AUY 922 has been shown to bind with high affinity to and inhibit Hsp90, resulting in the proteasomal degradation of oncogenic client proteins; the inhibition of cell proliferation; and the elevation of heat shock

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