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4-tetrahydropteridin-4-one
BM635 hydrochloride has an MIC50 of 0
E3 ligase Ligand-Linker Conjugates 4 together with JQ1 triggers the intracellular destruction of BET proteins
It acts to stabilize HIF-1α expression at normal oxygen tensions in cultured cells
TAS6417 alaxyl-M 4-tetrahydropteridin-4-oneTAS6417 (CLN 081) is a highly effective, orally active and pan mutation selective EGFR tyrosine kinase inhibitor with a unique scaffold fitting into the ATP binding site of the EGFR hinge region, with IC50 values ranging from 1. 1 8. 0 nM. Product information CAS Number: 1661854 97 2 Molecular Weight: 396. 44 Formula: C23H20N6O Chemical Name: N [(8S) 4 amino 6 methyl 5 (quinolin 3 yl) 8H,9H pyrimido[5,4 b]indolizin 8 yl]prop 2 enamide Smiles:
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