Umbralisib Catalog No.:M20065-C EGFR inhibitor directly depolymerizes microtubules

EGFR inhibitor directly depolymerizes microtubules and is used as a chemical probe to investigate both the EGFR pathway and microtubule dynamics

InChiKey: LQKQLKMTJOMCMJ-UHFFFAOYSA-N

InChiKey: FEQSYBHDHIPRKS-QWNZGVGBSA-N

51(6):1831-41

Umbralisib Catalog No.:M20065-C EGFR inhibitor directly depolymerizes microtubulesUmbralisib (TGR 1202) is a novel PI3K inhibitor, with IC50 and EC50 of 22. 2 nM and 24. 3 nM, respectively; Umbralisib (TGR 1202) is also active against CK1, with an EC50 value of 6. 0 M. Product information CAS Number: 1532533 67 7 Molecular Weight: 571. 55 Formula: C31H24F3N5O3 Chemical Name: 2 [(1S) 1 {4 amino 3 [3 fluoro 4 (propan 2 yloxy)phenyl] 1H pyrazolo[3,4 d]pyrimidin 1 yl}ethyl] 6 fluoro 3 (3 fluorophenyl) 4H chromen 4 one Smiles: