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CAS Number: 265129-71-3
antineoplastic and anti-fibrotic activities
11(5):524-34
InChiKey: XDAOLTSRNUSPPH-XMMPIXPASA-N
SR-717 lithium - CAS# 2375421-09-1 60295 CAS Number: 265129-71-3SR 717 lithium, CAS No. 2375421 09 1, is an agonist of stimulator of interferon genes STING for treating cancer. SR 717 demonstrates broad interspecies and interallelic specificity. SR 717 functions as a direct cyclic guanosine monophosphate adenosine monophosphate (cGAMP) mimetic that induces the same "closed" conformation of STING. SR 717 displayed antitumor activity; promoted the activation of CD8+ T, natural killer, and dendritic cells in relevant