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It is a σ1 receptor agonist with 5% of its SRI potency
Chemical Name: 2-{4'-carbamoyl-[1
Guanidine hydrochloride also reduces the ability of Hsp104 to restore activity of thermally denatured luciferase
7-dioxaspiro[5
Icenticaftor tor II It is a σ1 receptorIcenticaftor (QBW251) is an orally active CFTR channel potentiator, with EC50s of 79 nM and 497 nM for F508del and G551D CFTR, respectively. Icenticaftor can be used for chronic obstructive pulmonary disease (COPD) and cystic fibrosis research. Product information CAS Number: 1334546 77 8 Molecular Weight: 361. 24 Formula: C12H13F6N3O3 Chemical Name: 3 amino 6 methoxy N [(2S) 3,3,3 trifluoro 2 hydroxy 2 methylpropyl] 5 (trifluoromethyl)pyridine 2