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137 nM (β-C1B)
Molecular Weight: 1067
AT13148 inhibits a panel of kinases at 10 μM
pii: S1470-2045(14)71135-0
Embelin 312 137 nM (β-C1B)Apomorphine Hydrochloride, also known as APL 130277 and TAK 251, is a dopamine D2 agonist used for the treatment of Parkinson's disease. Apomorphine also promotes intraneuronal amyloid (A) degradation and improves memory function in an Alzheimer's disease model. Protein levels of two types of serine phosphorylated insulin receptor substrate 1 (IRS 1), pS616 and pS636 639, significantly decreased following Apomorphine treatment in the 13 month old 3xTg
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