Dxd 935 7-4-2-1-3(6-4)5(8)9/h2

7-4-2-1-3(6-4)5(8)9/h2

thereby restoring Jun kinase and MAPK pathway activities and promoting MAPK-mediated cellular proliferation and differentiation pathways

CAS Number: 490-78-8

Chemical Name: (3-Amino-1-hydroxypropane-1

Dxd 935 7-4-2-1-3(6-4)5(8)9/h2Dxd (Exatecan derivative for ADC) is a potent DNA topoisomerase I inhibitor, with an IC50 of 0. 31 M, used as a conjugated drug of HER2 targeting ADC (DS 8201a). Product information CAS Number: 1599440 33 1 Molecular Weight: 493. 48 Formula: C26H24FN3O6 Synonym: Exatecan derivative for ADC Chemical Name: N [(10S, 23S) 10 ethyl 18 fluoro 10 hydroxy 19 methyl 5, 9 dioxo 8 oxa 4, 15 diazahexacyclo[14. 7. 1. 0, . 0, . 0, . 0, ]tetracosa 1, 6(11), 12, 14,