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TMRM Catalog No.:M32897-C TPX-0131 potently inhibits wild-type ALK

SKU: 31975795682

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Description

TPX-0131 potently inhibits wild-type ALK (IC50 = 1

PG01 at 100 nM strongly stimulates channel activity with multiple channel openings observed

PROTAC Linker 1

Smiles: CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC1=CNC2=CC=CC=C12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(N)=O

TMRM Catalog No.:M32897-C TPX-0131 potently inhibits wild-type ALKTMRM is a cell permeant cationic lipophilic red fluorescent dye (ex=530 nm, em=592 nm). Product information CAS Number: 115532 49 5 Molecular Weight: 401. 48 Formula: C25H25N2O3 Chemical Name: 6 (dimethylamino) 9 [2 (methoxycarbonyl)phenyl] N,N dimethyl 3H xanthen 3 iminium Smiles: COC(=O)C1=CC=CC=C1C1C2=CC=C(C=C2OC2=CC(C=CC2=1)=[N+](C)C)N(C)C InChiKey: WAWRKBQQBUDAMY UHFFFAOYSA N InChi: InChI=1S C25H25N2O3 c1 26(2)16 10 12 20 22(14 16)30 23 15

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