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3-difluorocyclobutyl)-pyrazole derivatives as novel potent transforming growth factor-β type 1 receptor inhibitors
Harmine was dosed orally to obese db/db mice at 30 mg/kg
Like the allylamine antifungals
Alrefai WA
Duocarmycin DM free base lator 1 3-difluorocyclobutyl)-pyrazole derivatives as novel potentDuocarmycin DM free base, a DNA minor groove alkylator, is an antibody drug conjugates (ADCs) toxin. Duocarmycin DM free base is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity. Product information CAS Number: 1116745 06 2 Molecular Weight: 463. 96 Formula: C26H26ClN3O3 Chemical Name: (1S) 1 (chloromethyl) 3 {5 [2 (dimethylamino)ethoxy] 1H indole 2 carbonyl} 1H, 2H, 3H