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L-778123 hydrochloride Size:Contact [email protected] for quotation InChiKey: RQEBZJWSAAWCAV-UHFFFAOYSA-N

SKU: 21094554431

4.6
USD100.00 USD132.00

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Description

InChiKey: RQEBZJWSAAWCAV-UHFFFAOYSA-N

14(2):163-170

0) and a low-affinity antagonist of D2 receptor (pKi=6

CNS-penetrant

L-778123 hydrochloride Size:Contact [email protected] for quotation InChiKey: RQEBZJWSAAWCAV-UHFFFAOYSA-NL 778123 hydrochloride is an inhibitor of FPTase and GGPTase I with IC50 of 2 nM and 98 nM in enzyme inhibition determination. IC50 value: 2 nM Target: FPTasein vitro: L 778123 can completely inhibit Ki Ras prenylation. L 778123 as a farnesyltransferase inhibitor can have a good cytotoxic activity as a classic anti cancer agent. in vivo: In the dog model, L 778123 inhibits HDJ2 prenylation and produces measurable, albeit slight (5%), levels of

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