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InChi: InChI=1S/C30H37N7O2/c1-39-25-12-13-27-23(20-25)21-26(30(38)31-27)28(36-18-16-35(17-19-36)24-10-6-3-7-11-24)29-32-33-34-37(29)15-14-22-8-4-2-5-9-22/h2
424(1):47-60
NS309 is a nonselective activator of small- and intermediate-conductance Ca2+-activated K+ (SK/KCa2 and IK/KCa3
(2015) Oncotarget
2-Phenyl-2-(1-piperidinyl)propane 0259 InChi: InChI=1S/C30H37N7O2/c1-39-25-12-13-27-23(20-25)21-26(30(38)31-27)28(36-18-16-35(17-19-36)24-10-6-3-7-11-24)29-32-33-34-37(29)15-14-22-8-4-2-5-9-22/h2KI: 11 microM for 7 (benzyloxy)resorufin O dealkylation activity of liver microsomes obtained from phenobarbital induced rats 2 Phenyl 2 (1 piperidinyl)propane is a mechanism based inactivator of human cytochrome P450 (CYP) 2B6. The use of selective chemical inhibitors of human cytochrome P450 enzymes is a powerful method by which the relative contributions of different human P450 enzymes to the drug metabolism can be obtained. However, the