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The EC50 for Cdc42 wild type and Cdc42Q61L mutant were 2
and inhibits IClCa in RUICC without significantly affecting L-type Ca2+ current
PubMed PMID: 19338769
Smiles: NCC(CS(O)(=O)=O)C1C=CC(Cl)=CC=1
Torin 2 Catalog No.:M10889-2 The EC50 for Cdc42 wildTorin 2 is a novel, second generation ATP competitive inhibitor that is potent and selective for mTOR with a superior pharmacokinetic profile to previous inhibitors ((EC50 = 0. 3 nM). It has been shown that Torin 2 displayed dramatic antiproliferative activity across a panel of cancer cell lines. Torin 2 showed a powerful cytotoxic activity, inhibiting the growth of each cell line in a dose dependent manner, with an IC in the nanomolar range. Torin 2
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