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2]octan-3-yl (1S)-1-phenyl-1
BX-912 rimethobenzamide D6 2]octan-3-yl (1S)-1-phenyl-1BX912 is a selective potent PDK1 inhibitor with IC50 of 12 nM. BX912 blocks PDK1 Akt signaling in tumor cells and suppresses the anchorage dependent growth of a variety of tumor cell lines (such as PC 3 cells) in culture or induces apoptosis. Product information CAS Number: 702674 56 4 Molecular Weight: 471. 35 Formula: C20H23BrN8O Chemical Name: N {3 [(5 bromo 4 {[2 (1H imidazol 5 yl)ethyl]amino}pyrimidin 2 yl)amino]phenyl}pyrrolidine 1 carboxamide
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