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treatment with Ponatinib (AP24534) prolongs survival in a dose-dependent manner
10-epiminodibenzo[a
and exhibits low toxicity
2006 Jan 6
CGP71683 hydrochloride 294 treatment with Ponatinib (AP24534) prolongsCGP71683 hydrochloride (CGP71683A) is a competitive and sellective neuropeptide Y receptor type 5 (Y5 receptor) antagonist with Ki of 1. 3 nM. Product information CAS Number: 192322 50 2 Molecular Weight: 512. 07 Formula: C26H30ClN5O2S Chemical Name: N (((1r,4r) 4 (((4 aminoquinazolin 2 yl)amino)methyl)cyclohexyl)methyl)naphthalene 1 sulfonamide hydrochloride Smiles: Cl. NC1=NC(NC[C@@H]2CC[C@@H](CNS(=O)(=O)C3=CC=CC4=CC=CC=C43)CC2)=NC2=CC=CC=C21