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Specificity and mechanism of action of EHT 1864
Midostaurin for acute myeloid leukaemia
18(9):2502-14
Chemical Name: 7-(4-(3-ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide
SB216763 - CAS# 280744-09-4 60255 Specificity and mechanism of actionSB 216763, CAS No. 280744 09 4, is a glycogen synthase kinase 3 (GSK3) inhibitor, which can maintain mouse embryonic stem cells (mESCs) in a pluripotent state in the absence of exogenous leukemia inhibitory factor (LIF) when cultured on mouse embryonic fibroblasts (MEFs). SB 216763 is the first GSK3 inhibitor that can promote self renewal of mESC co cultured with MEFs for more than two months. Product information CAS Number: 280744 09 4 Molecular
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