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is a potent EGFR inhibitor with Ki and IC50 of 6 and 25 pM
Formula: C29H27F5N2O6S
Molecular Weight: 1747
Smiles: CC(C)N1C=C(C2=CC=NC(NC[C@H](C)NC(=O)OC)=N2)C(=N1)C1=CC(Cl)=CC(NS(C)(=O)=O)=C1F
BML-210 Catalog No.:M12478-10 is a potent EGFR inhibitorBML 210 is a novel HDAC inhibitor, and its mechanism of action has not been characterized. IC50 value: 5 M Target: HDAC4 In vitro: Cell cycle analysis indicated that HeLa cell treatment with 20 and 30 M concentration of BML 210 increased the proportion of cells in G0 G1 phase, and caused accumulation in subG1, indicating that the cells are undergoing apoptosis. BML 210 inhibits the growth of NB4 cells in dose and time dependent manner. Product
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