MK-0429 ide) and inhibits LTB4-induced contraction of

and inhibits LTB4-induced contraction of lung parenchyma (pA2 = 7

Nonactin selectively induces apoptosis in cell lines harboring active mutant β-catenin

Quaternary amine compounds and antibody-drug conjugates thereof

topoisomerase II inhibitors and platinum derivatives

MK-0429 ide) and inhibits LTB4-induced contraction ofMK 0429 (L 000845704) is an orally active, potent, selective and nonpeptide pan integrin antagonist with IC50 values of 1. 6 nM, 2. 8 nM, 0. 1 nM, 0. 7 nM, 0. 5 nM and 12. 2 nM for v1, v3, v5, v6, v8 and 51, respectively. Product information CAS Number: 227963 15 7 Molecular Weight: 439. 51 Formula: C23H29N5O4 Chemical Name: (3S) 3 (6 methoxypyridin 3 yl) 3 {2 oxo 3 [3 (5,6,7,8 tetrahydro 1,8 naphthyridin 2 yl)propyl]imidazolidin 1 yl}propanoic acid