MARK-IN-1 fluorophenyl)-2-hydroxy-1-methyl-3-(1H-1 2 4-triazol-1-yl)propyl]benzamide-d3 Solubility: ≥ 22

Solubility: ≥ 22

1-1 mg/kg) reduces immobility time in the mouse tail suspension test (TST) at 1 mg/kg

Virtually complete inhibition of histamine release occurs at 100 μM

5)44-29)36(19

MARK-IN-1 fluorophenyl)-2-hydroxy-1-methyl-3-(1H-1 2 4-triazol-1-yl)propyl]benzamide-d3 Solubility: ≥ 22MARK IN 1 is a potent microtubule affinity regulating kinase (MARK) inhibitor with an IC50 of <0. 25 nM. Product information CAS Number: 1109283 93 3 Molecular Weight: 471. 53 Formula: C22H23F2N7OS Chemical Name: N [(1R,6R) 6 amino 2,2 difluorocyclohexyl] 5 methyl 4 [6 (1 methyl 1H pyrazol 4 yl)pyrazolo[1,5 a]pyrimidin 3 yl]thiophene 2 carboxamide Smiles: CN1C=C(C=N1)C1=CN2N=CC(=C2N=C1)C1C=C(SC=1C)C(=O)N[C@@H]1[C@H](N)CCCC1(F)F InChiKey: